中文名稱:MRPL48 抗原(重組蛋白)
英文名稱: MRPL48 Antigen (Recombinant Protein)
別 名: mitochondrial ribosomal protein L48; L48MT; CGI-118; HSPC290; MRP-L48
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 29-212 amino acids of human MRPL48 |
Full name: |
mitochondrial ribosomal protein L48 |
Synonyms: |
L48MT; CGI-118; HSPC290; MRP-L48 |
Swissprot: |
Q96GC5 |
Gene Accession: |
BC009764 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |