Background: |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. |
Applications: |
WB, IHC |
Name of antibody: |
DPYSL2(Ab-509) |
Immunogen: |
Synthesized non-phosphopeptide derived from human CRMP-2 around the phosphorylation site of threonine 509 (S-V-T(p)-P-K). |
Full name: |
dihydropyrimidinase-like 2 |
Synonyms: |
DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2 |
SwissProt: |
Q16555 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
62 kDa |
WB Positive control: |
HT-29 cells treated with heat shock lysate |
WB Recommended dilution: |
500-3000 |