中文名稱: 兔抗DPYD多克隆抗體
Background: |
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
DPYD |
Immunogen: |
Full length fusion protein |
Full name: |
dihydropyrimidine dehydrogenase |
Synonyms: |
DHP; DPD; DHPDHASE |
SwissProt: |
Q12882 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |