中文名稱：兔抗DPM1多克隆抗體

英文名稱： Anti-DPM1 rabbit polyclonal antibody

別名： MPDS; CDGIE

相關(guān)類別： 一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： DPM1

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

DPM1

Immunogen:

Full length fusion protein

Full name:

dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit

Synonyms:

MPDS; CDGIE

SwissProt:

O60762

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

20-100

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兔抗DPM1多克隆抗體

Background:	Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
Applications:	ELISA, IHC
Name of antibody:	DPM1
Immunogen:	Full length fusion protein
Full name:	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
Synonyms:	MPDS; CDGIE
SwissProt:	O60762
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human brain
IHC Recommend dilution:	20-100