Background: |
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. |
Applications: |
ELISA, WB |
Name of antibody: |
DNM1 |
Immunogen: |
Synthetic peptide of human DNM1 |
Full name: |
dynamin 1 |
Synonyms: |
DNM |
SwissProt: |
Q05193 |
ELISA Recommended dilution: |
1000-10000 |
WB Predicted band size: |
98 kDa |
WB Positive control: |
Mouse brain tissue |
WB Recommended dilution: |
200-1000 |