Background: |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). |
Applications: |
WB |
Name of antibody: |
DNM1L(Phospho-Ser637) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1. |
Full name: |
dynamin 1-like |
Synonyms: |
DLP1; DRP1; DVLP; EMPF; DYMPLE; HDYNIV |
SwissProt: |
O00429 |
WB Predicted band size: |
82 kDa |
WB Positive control: |
Jurkat cells and K562 cells lysates |
WB Recommended dilution: |
500-1000 |