中文名稱(chēng):GPBP1抗原(重組蛋白)
英文名稱(chēng): GPBP1 Antigen (Recombinant Protein)
別 名: GPBP; SSH6; VASCULIN
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概 述:
Fusion protein corresponding to a region derived from 293-473 amino acids of human GPBP1 |
Full name: |
GC-rich promoter binding protein 1 |
Synonyms: |
GPBP; SSH6; VASCULIN |
Swissprot: |
Q86WP2 |
Gene Accession: |
BC000267 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |