Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. |
Applications: |
ELISA, IHC |
Name of antibody: |
DKK3 |
Immunogen: |
Fusion protein of human DKK3 |
Full name: |
dickkopf WNT signaling pathway inhibitor 3 |
Synonyms: |
RIG; REIC |
SwissProt: |
Q9UBP4 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer and human gastric cancer |
IHC Recommend dilution: |
25-100 |