中文名稱:CALCOCO1 抗原(重組蛋白)
英文名稱: CALCOCO1 Antigen (Recombinant Protein)
別 名: calcium binding and coiled-coil domain 1; Cocoa; PP13275; calphoglin
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 492-691 amino acids of human CALCOCO1 |
Full name: |
calcium binding and coiled-coil domain 1 |
Synonyms: |
Cocoa; PP13275; calphoglin |
Swissprot: |
Q9P1Z2 |
Gene Accession: |
BC003177 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3. |