中文名稱:AP1S3抗原(重組蛋白)
英文名稱: AP1S3 Antigen (Recombinant Protein)
別 名: PSORS15
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-104 amino acids of human AP1S3 |
Full name: |
adaptor related protein complex 1 subunit sigma 3 |
Synonyms: |
PSORS15 |
Swissprot: |
Q96PC3 |
Gene Accession: |
BC021898 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants. |