中文名稱:SETDB1抗原(重組蛋白)
英文名稱: SETDB1 Antigen (Recombinant Protein)
別 名: ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-200 amino acids of human SETDB1 |
Full name: |
SET domain bifurcated 1 |
Synonyms: |
ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4 |
Swissprot: |
Q15047 |
Gene Accession: |
BC009362 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. |