中文名稱:RBFOX2抗原(重組蛋白)
英文名稱: RBFOX2 Antigen (Recombinant Protein)
別 名: RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 191-390 amino acids of human RBFOX2 |
Full name: |
RNA binding fox-1 homolog 2 |
Synonyms: |
RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3 |
Swissprot: |
O43251 |
Gene Accession: |
BC013115 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. |