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  • PSMD12 抗原(重組蛋白)

    規(guī)格:
    數(shù)量:

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    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18374
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱(chēng):PSMD12 抗原(重組蛋白)

英文名稱(chēng): PSMD12 Antigen (Recombinant Protein)

別      名: proteasome 26S subunit, non-ATPase 12; p55; Rpn5; STISS

儲(chǔ)      存 冷凍(-20℃)

相關(guān)類(lèi)別:

概      述:

Fusion protein corresponding to a region derived from 257-456 amino acids of human PSMD12


技術(shù)規(guī)格:

Full name:

proteasome 26S subunit, non-ATPase 12

Synonyms:

p55; Rpn5; STISS

Swissprot:

O00232

Gene Accession:

BC019062

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


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