中文名稱:PRKAG2抗原(重組蛋白)
英文名稱: PRKAG2 Antigen (Recombinant Protein)
別 名: AAKG; CMH6; WPWS; AAKG2; H91620p
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 370-569 amino acids of human PRKAG2 |
Full name: |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
Synonyms: |
AAKG; CMH6; WPWS; AAKG2; H91620p |
Swissprot: |
Q9UGJ0 |
Gene Accession: |
BC020540 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |