購物車
幫助
021-54845833/15800441009
中文名稱：PPM1B抗原（重組蛋白）
英文名稱 PPM1B Antigen (Recombinant Protein)
別 名： PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 288-479 amino acids of human PPM1B |
技術規格：
|
Full name: |
protein phosphatase, Mg2+/Mn2+ dependent 1B |
|
Synonyms: |
PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X |
|
Swissprot: |
O75688 |
|
Gene Accession: |
BC012002 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. |
