中文名稱:PDIA5 抗原(重組蛋白)
英文名稱: PDIA5 Antigen (Recombinant Protein)
別 名: protein disulfide isomerase family A member 5; PDIR
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 22-262 amino acids of human PDIA5 |
Full name: |
protein disulfide isomerase family A member 5 |
Synonyms: |
PDIR |
Swissprot: |
Q14554 |
Gene Accession: |
BC001625 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants. |