中文名稱:OVOL2 抗原(重組蛋白)
英文名稱: OVOL2 Antigen (Recombinant Protein)
別 名: ovo like zinc finger 2; CHED; CHED1; CHED2; PPCD1; ZNF339; EUROIMAGE566589
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-275 amino acids of human OVOL2 |
Full name: |
ovo like zinc finger 2 |
Synonyms: |
CHED; CHED1; CHED2; PPCD1; ZNF339; EUROIMAGE566589 |
Swissprot: |
Q9BRP0 |
Gene Accession: |
BC006148 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy. |