中文名稱(chēng): MCPH1 抗原(重組蛋白)
英文名稱(chēng): MCPH1 Antigen (Recombinant Protein)
別 名: microcephalin 1; MCT; BRIT1
相關(guān)類(lèi)別: 抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Fusion protein corresponding to a region derived from 363-562 amino acids of human MCPH1 |
Full name: |
microcephalin 1 |
Synonyms: |
MCT; BRIT1 |
Swissprot: |
Q8NEM0 |
Gene Accession: |
BC030702 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. |