中文名稱: LTA4H 抗原(重組蛋白)
英文名稱: LTA4H Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
別 名: leukotriene A4 hydrolase
相關類別: 抗原
概 述
Fusion protein corresponding to a region derived from 251-511 amino acids of human LTA4H |
Full name: |
leukotriene A4 hydrolase |
Swissprot: |
P09960 |
Gene Accession: |
BC032528 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein. |