購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MDM2多克隆抗體
英文名稱： Anti-MDM2 rabbit polyclonal antibody
別 名： HDMX; hdm2; ACTFS
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： MDM2
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 . Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 . Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 . |
|
Applications: |
WB |
|
Name of antibody: |
MDM2 |
|
Immunogen: |
Synthetic peptide of human MDM2 |
|
Full name: |
MDM2 oncogene, E3 ubiquitin protein ligase |
|
Synonyms： |
HDMX; hdm2; ACTFS |
|
SwissProt: |
Q00987 |
|
WB Predicted band size: |
90 kDa |
|
WB Positive control: |
293 and Hela cells |
|
WB Recommended dilution: |
500-1000 |
