中文名稱:KRT2抗原(重組蛋白)
英文名稱: KRT2 Antigen (Recombinant Protein)
儲 存:冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to a region derived from 233-487 amino acids of human KRT2 |
Full name: |
keratin 2 |
Synonyms: |
K2e, KRTE, CK-2e, KRT2A, KRT2E |
Swissprot: |
P35908 |
Gene Accession: |
BC096294 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. |