中文名稱: KARS1 抗原(重組蛋白)
英文名稱: KARS1 Antigen (Recombinant Protein)
別 名: lysyl-tRNA synthetase 1; KRS; KARS; KARS2; CMTRIB; DFNB89
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述
Fusion protein corresponding to a region derived from 348-597 amino acids of human KARS1 |
Full name: |
lysyl-tRNA synthetase 1 |
Synonyms: |
KRS; KARS; KARS2; CMTRIB; DFNB89 |
Swissprot: |
Q15046 |
Gene Accession: |
BC004132 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |