中文名稱: ITLN1 抗原(重組蛋白)
英文名稱: ITLN1 Antigen (Recombinant Protein)
別 名: intelectin 1 (galactofuranose binding); HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
儲 存: 冷凍(-20℃)
相關類別: 抗原
概述
Fusion protein corresponding to a region derived from 19-298 amino acids of human ITLN1 |
Full name: |
intelectin 1 (galactofuranose binding) |
Synonyms: |
HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin |
Swissprot: |
Q8WWA0 |
Gene Accession: |
BC020664 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. |