中文名稱: ITGAE 抗原(重組蛋白)
英文名稱: ITGAE Antigen (Recombinant Protein)
別 名: integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); CD103; HUMINAE
儲 存: 冷凍(-20℃)
相關類別: 抗原
概述
Fusion protein corresponding to a region derived from 19-177 amino acids of human ITGAE |
Full name: |
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
Synonyms: |
CD103; HUMINAE |
Swissprot: |
P38570 |
Gene Accession: |
BC113436 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. |