中文名稱:IRF8抗原(重組蛋白)
英文名稱: IRF8 Antigen (Recombinant Protein)
別 名: ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP
儲 存: 冷凍(-20℃)
相關類別: 抗原
概述
Fusion protein corresponding to a region derived from 127-426 amino acids of human IRF8 |
Full name: |
interferon regulatory factor 8 |
Synonyms: |
ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP |
Swissprot: |
Q02556 |
Gene Accession: |
BC126247 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. |