中文名稱: ING5 抗原(重組蛋白)
英文名稱: ING5 Antigen (Recombinant Protein)
別 名: inhibitor of growth family, member 5; p28ING5
相關類別: 抗原
儲 存: 冷凍(-20℃)
概述
Fusion protein corresponding to N terminal 226 amino acids of human ING5 |
Full name: |
inhibitor of growth family, member 5 |
Synonyms: |
p28ING5 |
Swissprot: |
Q8WYH8 |
Gene Accession: |
BC005370 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. |