Name: PCID2抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PCID2抗原（重組蛋白）

英文名稱： PCID2 Antigen (Recombinant Protein)

別名： PCI domain containing 2; F10

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to C terminal 200 amino acids of human PCID2

技術規(guī)格

Full name:	PCI domain containing 2
Synonyms:	F10
Swissprot:	Q5JVF3
Gene Accession:	BC016614
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).

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