中文名稱: IL27RA 抗原(重組蛋白)
英文名稱: IL27RA Antigen (Recombinant Protein)
別 名: interleukin 27 receptor, alpha; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
儲 存: 冷凍(-20℃)
相關類別: 抗原
概述
Fusion protein corresponding to a region derived from 319-507 amino acids of human IL27RA |
Full name: |
interleukin 27 receptor, alpha |
Synonyms: |
CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1 |
Swissprot: |
Q6UWB1 |
Gene Accession: |
BC028003 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. |