中文名稱: 兔抗ALS2多克隆抗體
英文名稱: Anti-ALS2 rabbit polyclonal antibody
別 名: ALSJ; PLSJ; IAHSP; ALS2CR6
相關類別: 一抗
儲 存: 冷凍(-20℃)
抗 原: ALS2
宿 主: Rabbit
反應種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
ALS2 |
Immunogen: |
Fusion protein of human ALS2 |
Full name: |
amyotrophic lateral sclerosis 2 (juvenile) |
Synonyms: |
ALSJ; PLSJ; IAHSP; ALS2CR6 |
SwissProt: |
Q96Q42 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |