中文名稱:YARS2抗原(重組蛋白)
英文名稱: YARS2 Antigen (Recombinant Protein)
別 名: TYRRS; CGI-04; MLASA2; MT-TYRRS
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 300 amino acids of human YARS2 |
Full name: |
tyrosyl-tRNA synthetase 2, mitochondrial |
Synonyms: |
TYRRS; CGI-04; MLASA2; MT-TYRRS |
Swissprot: |
Q9Y2Z4 |
Gene Accession: |
BC015625 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). |