中文名稱: TSC22D3抗原(重組蛋白)
英文名稱: TSC22D3 Antigen (Recombinant Protein)
別 名: DIP; GILZ; hDIP; DSIPI; TSC-22R
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 58-134 amino acids of human TSC22D3 |
Full name: |
TSC22 domain family, member 3 |
Synonyms: |
DIP; GILZ; hDIP; DSIPI; TSC-22R |
Swissprot: |
Q99576 |
Gene Accession: |
BC018148 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene. |