中文名稱:TRAFD1 抗原(重組蛋白)
英文名稱: TRAFD1 Antigen (Recombinant Protein)
別 名: TRAF-type zinc finger domain containing 1; FLN29
儲 存: 冷凍(-20℃)
相關類別:抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human TRAFD1 |
Full name: |
TRAF-type zinc finger domain containing 1 |
Synonyms: |
FLN29 |
Swissprot: |
O14545 |
Gene Accession: |
BC003553 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. |