中文名稱:兔抗ALPL多克隆抗體
英文名稱: Anti-ALPL rabbit polyclonal antibody
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
抗 原: ALPL
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. |
Applications: |
ELISA, IHC |
Name of antibody: |
ALPL |
Immunogen: |
Fusion protein of human ALPL |
Full name: |
alkaline phosphatase, biomineralization associated |
Synonyms: |
HOPS; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP |
SwissProt: |
P05186 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer and Human liver cancer |
IHC Recommend dilution: |
200-400 |