中文名稱:TNFRSF9抗原(重組蛋白)
英文名稱: TNFRSF9 Antigen (Recombinant Protein)
別 名: ILA; 4-1BB; CD137; CDw137
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 24-186 amino acids of human TNFRSF9 |
Full name: |
TNF receptor superfamily member 9 |
Synonyms: |
ILA; 4-1BB; CD137; CDw137 |
Swissprot: |
Q07011 |
Gene Accession: |
BC006196 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |