Fusion protein corresponding to a region derived from 332-538 amino acids of human RBBP5 |
技術規格
Full name: |
retinoblastoma binding protein 5 |
Synonyms: |
RBQ3; SWD1 |
Swissprot: |
Q15291 |
Gene Accession: |
BC053856 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |