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中文名稱：兔抗ALOXE3多克隆抗體
英文名稱： Anti-ALOXE3 rabbit polyclonal antibody
別 名： arachidonate lipoxygenase 3; ARCI3; E-LOX; eLOX3; eLOX-3
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： ALOXE3
反應(yīng)種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ALOXE3 |
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Immunogen: |
Fusion protein of human ALOXE3 |
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Full name: |
arachidonate lipoxygenase 3 |
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Synonyms: |
ARCI3; E-LOX; eLOX3; eLOX-3 |
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SwissProt: |
Q9BYJ1 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
80 kDa |
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WB Positive control: |
Mouse kidney tissue lysate |
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WB Recommended dilution: |
200-1000 |
