中文名稱:SERPINA3 抗原(重組蛋白)
英文名稱: SERPINA3 Antigen (Recombinant Protein)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 300 amino acids of human SERPINA3 |
技術規格:
Full name: |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
Synonyms: |
ACT; AACT; GIG24; GIG25 |
Swissprot: |
P01011 |
Gene Accession: |
BC034554 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. |