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中文名稱：PIKFYVE抗原（重組蛋白）
英文名稱： PIKFYVE Antigen (Recombinant Protein)
概 述：
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Fusion protein corresponding to C terminal 300 amino acids of human PIKFYVE |
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Full name: |
phosphoinositide kinase, FYVE finger containing |
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Synonyms: |
CFD; FAB1; HEL37; PIP5K; PIP5K3; ZFYVE29 |
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Swissprot: |
Q9Y2I7 |
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Gene Accession: |
BC032389 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKFYVEe; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. |
