中文名稱:PFKP抗原(重組蛋白)
英文名稱: PFKP Antigen (Recombinant Protein)
別 名: PFKF; PFK-C
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human PFKP |
Full name: |
phosphofructokinase, platelet |
Synonyms: |
PFKF; PFK-C |
Swissprot: |
Q01813 |
Gene Accession: |
BC002536 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2 |