中文名稱: IL2RB抗原(重組蛋白)
英文名稱: IL2RB Antigen (Recombinant Protein)
別 名: CD122; IL15RB; P70-75
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 41-240 amino acids of human IL2RB |
Full name: |
interleukin 2 receptor, beta |
Synonyms: |
CD122; IL15RB; P70-75 |
Swissprot: |
P14784 |
Gene Accession: |
BC025691 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. |