中文名稱: HSD17B4抗原(重組蛋白)
英文名稱: HSD17B4 Antigen (Recombinant Protein)
別 名: DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 484-736 amino acids of human HSD17B4 |
Full name: |
hydroxysteroid (17-beta) dehydrogenase 4 |
Synonyms: |
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1 |
Swissprot: |
P51659 |
Gene Accession: |
BC003098 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. |