Name: MED28抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MED28抗原（重組蛋白）

英文名稱： MED28 Antigen (Recombinant Protein)

別名： EG1; magicin; 1500003D12Rik

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 1-178 amino acids of human MED28

技術規格

Full name:	mediator complex subunit 28
Synonyms:	EG1; magicin; 1500003D12Rik
Swissprot:	Q9H204
Gene Accession:	BC011936
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.

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