中文名稱: GCKR抗原(重組蛋白)
英文名稱: GCKR Antigen (Recombinant Protein)
別 名: GKRP; FGQTL5
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 90-286 amino acids of human GCKR |
Full name: |
glucokinase (hexokinase 4) regulator |
Synonyms: |
GKRP; FGQTL5 |
Swissprot: |
Q14397 |
Gene Accession: |
BC130481 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). |