中文名稱: FLI1抗原(重組蛋白)
英文名稱: FLI1 Antigen (Recombinant Protein)
別 名: EWSR2; SIC-1; BDPLT21
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 203-452 amino acids of human FLI1 |
Full name: |
Fli-1 proto-oncogene, ETS transcription factor |
Synonyms: |
EWSR2; SIC-1; BDPLT21 |
Swissprot: |
Q01543 |
Gene Accession: |
BC001670 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |