中文名稱: FCGR2B抗原(重組蛋白)
英文名稱: FCGR2B Antigen (Recombinant Protein)
別 名: CD32; FCG2; CD32B; FCGR2; IGFR2
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 54-217 amino acids of human FCGR2B |
Full name: |
Fc fragment of IgG, low affinity IIb, receptor (CD32) |
Synonyms: |
CD32; FCG2; CD32B; FCGR2; IGFR2 |
Swissprot: |
P31994 |
Gene Accession: |
BC031992 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. |