中文名稱: EPSTI1抗原(重組蛋白)
英文名稱: EPSTI1 Antigen (Recombinant Protein)
別 名: BRESI1
相關類別: 抗原
概 述:
Fusion protein corresponding to N terminal 300 amino acids of human EPSTI1 |
Full name: |
epithelial stromal interaction 1 |
Synonyms: |
BRESI1 |
Swissprot: |
Q96J88 |
Gene Accession: |
BC023660 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
EPSTI1 (Epithelial-stromal interaction protein 1), also known as BRESI1, is a 318 amino acid protein that is highly expressed in spleen, placenta, small intestine, liver, kidney, thymus, testis and salivary gland. Existing as three isoforms that are formed due to alternative splicing events, EPSTI1 is weakly expressed in normal breast tissue, but is heavily up-regulated in breast carcinoma, suggesting an important role for EPSTI1 in tumor formation and/or progression. Additionally, EPSTI1 is found in blood cells from systemic lupus erythematosus (SLE)-afflicted patients, implicating EPSTI1 as a potential protein involved in SLE. |