Name: EPS15L1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)：EPS15L1抗原（重組蛋白）

英文名稱(chēng)： EPS15L1 Antigen (Recombinant Protein)

別名： EPS15R

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human EPS15L1

技術(shù)規(guī)格：

Full name:	epidermal growth factor receptor pathway substrate 15-like 1
Synonyms:	EPS15R
Swissprot:	Q9UBC2
Gene Accession:	BC131590
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

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