Name: SIRT6抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： SIRT6抗原（重組蛋白）

英文名稱： SIRT6 Antigen (Recombinant Protein)

別名： SIR2L6

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 35-274 amino acids of human SIRT6

技術規格

Full name:	Sirtuin 6
Synonyms:	SIR2L6
Swissprot:	Q8N6T7
Gene Accession:	BC028220
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

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