中文名稱: EHHADH抗原(重組蛋白)
英文名稱: EHHADH Antigen (Recombinant Protein)
別 名: LBP; ECHD; LBFP; PBFE; L-PBE
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 283-572 amino acids of human EHHADH |
Full name: |
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
Synonyms: |
LBP; ECHD; LBFP; PBFE; L-PBE |
Swissprot: |
Q08426 |
Gene Accession: |
BC038948 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. |