Full name: |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
Synonyms: |
GDN; PI7; PN1; PNI; PI-7; PN-1; GDNPF |
Swissprot: |
P07093 |
Gene Accession: |
BC042628 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. |